This dissertation examines the stock-out of antiretrovirals in Uganda. It relates these stock-outs to the production of order and disorder - normalcy and crisis - in the AIDS epidemic. Between 2009 and 2011, numerous clinics in various places in Uganda were running out of antiretrovirals. The subsequent rationing of antiretrovirals gave rise to a number of ethical and moral dilemmas that will be discussed here in order to generalize more broadly on the social and scientific prerequisites of a ‘normal life’ with HIV. More than for other pharmaceuticals, the expectation that antiretrovirals can enable a ‘normal life’ with HIV, regardless of where one lives, is intricately linked with the trust that these life-prolonging medicines will be supplied permanently and without any interruptions. The stock-outs examined in this thesis show how people move between the AIDS crisis and normalcy by constantly fixing institutional mechanisms to scale-up access to treatment, maintain HIV as a chronic illness, and more importantly in dealing with the underlying scarcity of antiretrovirals. The continuous recalibration of treatment leads to a permanent reorganization of the AIDS crisis around the supply of antiretrovirals.