This paper's topic is based on a general interest for possibilities of myocarditic protection after preceding impairment. In turn, two alleged protectors, the reducing agents glutathion and ascorbic acid are verified for their potential of cardio-vascular protection in vitro. The so-called "Scavenger"- function of both reducing agents is thereby as a mechanism of action of the paper's main interest. In particular, the cardioprotective potential of the reducing agents in the case of an impairment of the heart prepatation by ischaemia/reperfusion, as well as by the noxes verapamil, pentobarbital, tetrachloromethane and kalium ion surplus are investigated. Easy models (‘Langendorff-heart', atrium-auricle-preparation) are used, in order to combine glutathion and ascorbic acid with various noxes in combined experiments. None of these experiments resulted in the detection of significant changes of the appropriate parameter, which could trigger a conclusion of cardioprotective effects of the reducing agents. Besides those findings, this paper discusses the inappropriateness of the research's predetermined methodological approach.