Human medical wastes belong to the category of hazardous wastes. Their infectious character requires a high safety level during collection, transport and disposal. At present the common disposal practise is to collect the waste at the point of emerges (hospitals) and the transport to local hazardous waste incineration plants. In most of the cases this is carried out by external service companies specialised in hazardous waste disposal. Thus, additional costs for handling, transport and conditioning of the waste occur. An on-site operating incineration system would safe these additional expenses since a third party don’t need to be involved in the disposal process. Therefore, the objective of this work was to development a compact plasma chemical waste treatment plant for the on-site incineration of infectious human medical waste. In order to meet the objective a waste agent was developed. The agent consists of a mixture of meat and bone meal, wood chips and water. By varying the individual fractions of the composition, it was possible to mimic the chemical and physical behaviour of the real medical waste (elemental composition, ash and water content, heat of combustion, viscosity, etc.). By means of a solid fuel characterisation study the thermal stability of the agent was investigated. A mass balance of the decomposition products was constructed and the decomposition kinetic was analysed. As a result of the decomposition study a particle combustion model was developed, were the kinetic and physical data obtained fed into. A mobile demonstrator plant for the plasma chemical incineration of human medical waste was designed, assembled and commissioned. A comprehensive set of test runs and sensitivity studies has been conducted in order to specify the stabile operation range. For the optimisation purpose, an optical segment of the tube reactor has been developed in order to analyse the disperse particles phase (residence time distribution) using a high speed camera system. A 3-dimensional CFD modelling of the thermal plasma reactor has been carried out and validated in order to improve the understanding of internal flow profile and to asses the mixing behaviour of the reactants. By means of the insights gained as a result of the characterisation work, it was possible to meet the requirements of the German regulation on the disposal of thermal treated waste of ≤5% weight loss on ignition. The specific energy input to achieve that level was approx. 2 kWh/kg. An economic analysis of the developed incineration process finalises the thesis.